Alexandra's Licence Portfolio
Model for Charcot-Marie Tooth Disease
MyoLoop is a device that simulates the synchronised mechanical and electrical events that occur in the heart inside the body (in vivo), on an in vitro heart model known as myocardial slice (MS). The system is self-contained, and designed for chronic experiments, that is culture of myocardial slices. MyoLoop can simulate pathological (e.g. hypertension), to study their progression, and the effects of therapeutic interventions on them.
A range of improved tetracycline inducible vectors to study the function of essential mycobacterial genes.
A portfolio of human colorectal adenocarcenoma cell lines including primary cell lines isolated from patients (of various Duke's stages and histological grades) in addition to cloned cells lines genetically modified to highly express alpha integrin domains.
A simple self-rating questionnaire for dependent personality features
8-question tool for quick assessment of social functioning. Validated in study of over 4,000 subjects.
A mouse model expressing human zinc transporter 8 (ZnT8), a protein of interest in diabetes research
Disease model for research into conditions involving complement factor H
POPDC1S191F zebrafish mutant
A well-established, validated and widely-used self-assessment scoring system used in a number of clinical trials involving benzodiazepines.