Available technologies

Wide Clip and Applicator for Minimally Invasive Surgery

Reference number: 6687

The technology relates to a novel rotative surgical clip and applicator that allows the clamping of large anatomical area for use in minimally invasive surgery.

Proposed use

  • Surgical device for minimally invasive surgery: (e.g., bariatric surgery, benign upper GI surgery, hepatobiliary surgery, colorectal surgery, thoracic surgery)
  • Reinforcement of staple line
  • Closure of enterotomy
  • Control of vascular/biliary pedicles
  • Facilitate retraction of large organs

Problem addressed

Laparoscopic surgery often a requires to clamp folds of tissue together to occlude the flow of blood or other fluids through anatomical lumens. The tissues are held together by surgical clips loaded into the jaw of an applicator. The clip applicators contain a magazine of surgical clips that can be fired in succession. A conventional laparoscopic clip applicator system deploys a clip that has a standard profile with a nominal width of only 1mm. Although these surgical clips are ideal for ligating tubular structures, they are not designed to compress significant areas of tissue. In addition, when conventional clips are loaded into the jaw that is longitudinal to the shaft of the instrument, it imposes a limit on the width of the clip to fit within the cross sectional footprint of the clip applicator. These challenges have been addressed by a novel innovative applicator that will enhance the functionality of the laparoscopic clip with greater performance in tissue compression.

Technology overview

The key features of this technology include:

  • The elongated clip with multiple bracings to allow for a greater degree of clamping force to be exerted on to the tissue being clamped together.
  • The clip is single-braced with a T profile for large-area clamping of surgical anatomy.
  • The bracing is aligned with the centreline of the clip applicator.
  • The clip applicator specifically designed using spring-loaded jaws and a tendon-based system to rotate the clip within the abdomen.
  • Clips demonstrated superior clamping force and increased burst pressure resistance to standard ligation clips in ex vivo testing

The design features improve clip retention, and ensure that the clip deforms in a controlled manner and it remains parallel under deformation. An additional consideration of a rotatable clipping system is the need for features that not only retain the clips in the jaws of the device but that also allows torque to be transmitted to the clip in order for it to be rotated in a controlled manner. Plus, the design also allows the use of clips of variable lengths.

Benefits Development stage
  • Enables the clamping of large anatomical area during minimal invasive surgery
  • The design of the clip applicator facilitating rotative move inside the body
  • The elongated design of the clip ensuring low deformity during clamping
  • Prototype applicator and clips have been developed
  • Initial ex vivo characterisation of the clips has been performed


Intellectual property information

Patents applications published as: WO2018069690A1; EP3525689A1 and US2020038029A1.

Link to published paper(s)

Erridge, S., Payne, C. and Sodergren, M., 2019. Novel clip applicator for minimally invasive surgery. Surgical Endoscopy, 33(8), pp.2710-2718. (https://link.springer.com/content/pdf/10.1007/s00464-019-06860-5.pdf)

Inventor information

Dr. Mikael Sodergren: Academic Clinical Lecturer in Surgery at Imperial College London with a special interest in clinical translation of innovative technology and novel surgical techniques.

Dr. Christopher Payne: Mechanical engineer and post-doctoral research fellow at Harvard University with an interest in technological innovation in minimally invasive surgery and medical robotics.

Download the datasheet


Nour Allouache

Industry Partnerships and Commercialisation Officer, Medicine


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