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Novel multifunctional bacteriophages

Researchers at Imperial College London have developed two novel modifications of bacteriophages to significantly improve their efficacy as vectors for targeted gene therapy, and exploit their advantages over eukaryotic viral vectors.

MicroRNA plasma markers for preterm labour

Suite of microRNAs for predicting cervical shortening and preterm birth that can be measured from blood samples taken in early pregnancy (from gestation week 12 onwards).

Novel protein fragment of von Willebrand’s factor for treating VWD and haemophilia A

Novel truncated fragments of von Willebrand factor (VWF) engineered by a team at Imperial College London.

Aptamer-based multiplex screening platform

A fully flexible, scalable and low-cost detection platform to sense multiple protein targets simultaneously by grafting specific sequences along the backbone of a double-stranded DNA carrier.

3D Printing with polygrain lattices

Enables the production of lightweight but tough and damage tolerant structures

Neural Network Wireless IoT Device

Over 3x energy saved vs standard wireless IoT sensor implementations.

Engini - Empowering Next Generation Implantable Neural Interfaces

ENGINI is a next generation neural implant technology for brain machine interfaces (BMIs) applicable to both central and peripheral nervous system

Smartphone Ballistocardiogram App

Smart phone Ballistocardiography (BCG) is a novel measurement method that requires fewer sensors (≥ 1) placed above the heart. It measures the physical movement of the chest due to the heart beating rather than electrical signals measured by ECG. Due to this neat mechanism, conductive gel is not required.

Voltage measurement for cancerous tissues

The novel technology can be used for real-time detection of cancerous tissue. This novel system measures voltage in tissue and differentiates cancerous from non-cancerous tissue. It could potentially be used as a portable theatre instrument or a hand-held device that enables testing of a wide range of cancerous tissue samples (ovarian, rectal sigmoid, spleen, para-aortic lymph node or pelvic side wall) during operation.

Endoscopic scanning probe device for rapid screening of hollow organs dysplasia

A robotic optical-biopsy scanning framework termed EndoDrone is proposed to improve the sensitivity of gastrointestinal (GI) endoscopy by automated scanning and real-time classification of wide tissue areas based on optical data. A “hot-spot” map is generated to highlight dysplastic or cancerous lesions for further scrutiny or concurrent resection. The device works as an add-on accessory to any conventional endoscope and to our knowledge is the first of its kind. The current functional prototype, which uses hyperspectral (HS) optical biopsy, is compatible with the anatomical dimensions of the colon, is envisaged to allow the identification of flat and small precancerous lesions that are currently missed.

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