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Charcot-Marie Tooth Disease model

Model for Charcot-Marie Tooth Disease

MicroRNA Biomarkers for ectopic or intrauterine pregnancy

MicroRNA are important gene regulators and their expression profiles change with pathophysiology, allowing their use as biomarkers. Imperial researchers have identified differential markers that can distinguish pregnancy of unknown location (PUL).

New handwashing solution to prevent spread of infectious diseases

This innovative technology proposes a new solution that improves handwashing practice and could help to prevent the spread of infectious diseases such as COVID-19, cholera and diarrhoea-related issues due to poor hygiene, especially in developing countries.

Transcutaneous fluorescence spectroscopy to assess gut permeability and gastric emptying rate

The present invention relates to a device and methods for non-invasive measurement of gut permeability and gastric empyting rate.

Self-disinfecting appliances

A novel device that can be fitted to home-care appliances to generate hydrogen peroxide or bleach, effectively producing a ‘self-cleaning’ appliance.

A novel dimer system for single small molecule detection

A new method for the efficient and accurate detection of proteins with nanopores by utilising aptamer-modified gold nanoparticle (AuNP) dimer carriers.

Hybrid nanopore opto-electronic platform for single molecule biological screening

A molecular beacon-modified DNA carrier to specifically identify short nucleic acids and small proteins using a synchronised opto-electronic platform with nanopipette.

Nanotweezers for single-cell biopsy

Inexpensive, easy to fabricate and use, dielectrophoretic nanotweezers for non-destructive subcellular concentration (trapping) and extraction of biomolecules.

DEP Trapping Using Metallised Nanopipettes

This invention enables efficient single molecule nanopore sensing at femtomolar concentrations using dielectrophoretic trapping by combining nanopore sensing and dielectrophoresis (DEP).

MyoLoop for cardiovascular research

MyoLoop is a device that simulates the synchronised mechanical and electrical events that occur in the heart inside the body (in vivo), on an in vitro heart model known as myocardial slice (MS). The system is self-contained, and designed for chronic experiments, that is culture of myocardial slices. MyoLoop can simulate pathological (e.g. hypertension), to study their progression, and the effects of therapeutic interventions on them.

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