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Novel phage/AAV delivery vector for gene therapy, medical imaging and vaccine delivery

The present invention relates to a novel DNA delivery vector for targeted gene therapy, medical imaging and vaccination with increased efficacy over existing technologies. The platform comprises a phagemid hybrid with phage and recombinant adeno-associated virus (AAV) components.

Novel large-scale method of production of AAVs

A novel viral delivery vector with scope for more cost-effective commercial production over existing technologies. The platform comprises a phagemid hybrid with recombinant adeno-associated virus (AAV) components.

Novel multifunctional bacteriophages

Researchers at Imperial College London have developed two novel modifications of bacteriophages to significantly improve their efficacy as vectors for targeted gene therapy, and exploit their advantages over eukaryotic viral vectors.

MicroRNA plasma markers for preterm labour

Suite of microRNAs for predicting cervical shortening and preterm birth that can be measured from blood samples taken in early pregnancy (from gestation week 12 onwards).

Novel protein fragment of von Willebrand’s factor for treating VWD and haemophilia A

Novel truncated fragments of von Willebrand factor (VWF) engineered by a team at Imperial College London.

Sensitive multiplex nanopore protein screening using aptamer-modified DNA carriers

A selective and sensitive approach to detect multiple proteins from complex biological samples.

3D Printing with polygrain lattices

Enables the production of lightweight but tough and damage tolerant structures

Neural Network Wireless IoT Device

Over 3x energy saved vs standard wireless IoT sensor implementations

Vary Gap

Low Weight Portable Wireless Power Transfer

Smart contracts written in quasi-natural language

Smart contracts that lawyers can program

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