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Portable device for skin contact and shear measurements

Portable and designed to minimise discomfort, this device measures the contact and shear characteristics of skin, with applications in a wide range of skin-object interactions.

Improved S1 antigen and SARS-CoV-2 antibody detection assay formats

An improved SARS-CoV-2 spike protein subunit (S1) antigen and two exceptional ELISA assay formats for highly specific and sensitive serological detection and measurement of antibodies to SARS-CoV-2

Management of pre-term labour via an application for pathway selective EP2 agonist

Imperial inventors have identified an EP2 receptor agonist with an application as a novel tocolytic for the management of pre-term labour. It is long-acting, inhibits contractility and does not activate pro-inflammatory pathways.

High-resolution transcription start site mapping using nanogram-levels of total RNA immunoprecipitation (SLIC-CAGE)

SLIC-CAGE is a novel development of the cap-trapper CAGE protocol which can generate complex high-quality libraries for as little as 5-10 nanograms of cellular RNA.

Octreotate Radioligand for Imaging Neuroendocrine Tumors

18F-FET-βAG-TOCA is a novel, ‘click’ 18F-labelled octreotate PET imaging radiopharmaceutical that detects tumour lesions in patients with neuroendocrine tumours (NETs).

Two distinct late stage preclinical lead series of highly specific inhibitors of MAP4K4

A late-stage, pre-clinically validated inhibitor of MAP4K4 for a range of indications including anthracycline cardiotoxicity

Two-gene signature diagnostic test for differentiating between viral and bacterial infections in children

A simple, whole blood 2-gene expression signature that distinguishes bacterial infection from both viral infection and childhood inflammatory diseases.

First-in-class drug candidate for treatment of multiple myeloma and Diffuse Large B Cell Lymphoma

DTP3 is a first-in-class GADD45β/MKK7 inhibitor targeting the NF-κB pathway

Novel apoptosis marker

A novel tracer, 18F-ICMT-11, targeting specific biological processes to improve detection of tumours that are often missed by FDG PET imaging

Advanced humidifier device

A novel, high capacity humidifying device which can rapidly humidify large spaces in seconds with multiple applications, including humidification and air purification.

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