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Machine learning tool stratifying early and late Alzheimer's disease (ApV)

A tool for predicting Alzheimer’s Disease (AD) with greater accuracy than conventional methods.

Deep learning cardiac motion analysis for survival prediction in heart failure

A tool for predicting survival outcomes in patients with pulmonary hypertension with greater accuracy than doctor’s measures

Human monoclonal antibodies to nCoV

A suite of broad neutralising monoclonal antibodies (bnMABs) isolated to be used for treatment of coronaviruses with a focus on SARS-CoV-2 (2019-nCoV). Four potential human monoclonal antibodies have been identified with broad neutralising activities in coronavirus (SARS and MERS).

Bio-Surfactant: a novel biobased surfactant

A surfactant produced from biobased chemicals that can replace petroleum-derived detergents, exhibiting higher performances in cleaning and resistance to hard water.

Methods to scale production of hPSC-derived endothelial cells

A novel 3D culture methodology using stirred-tank bioreactors as a scalable platform for the production of hPSC-derived endothelial cells.

ArterioWave - simple ultrasound-based diagnosis and monitoring of heart failure

ArterioWave is a novel ultrasound-based tool for screening and monitoring those at risk of, or suffering from, heart failure. It can be used by non-specialists and can be implemented on ultrafast or conventional scanners or handheld devices.

A cytokine for wound healing and scar reduction

A cytokine that promotes wound healing by accelerating re-epithelialization of the wound bed faster than FDA approved products. The treatment also has a potential to minimise scarring after injury

Active delivery of Zinc Fingers for in vivo enhancement of gene regulation

A universal method to enhance control of gene expression in vivo with artificial gene-regulatory transcription factors.

Zinc finger therapy for Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)

New zinc finger peptides and encoding nucleic acid molecules that can be used for the modulation of gene expression; this has therapeutic applications for neuro-degenerative disorders like FXTAS where altered expression of genes is part of the disease aetiology.

Zinc finger therapy for Amyotrophic lateral sclerosis (ALS) and Frontotemporal dementia (FTD)

New zinc finger peptides and encoding nucleic acid molecules that can be used for the modulation of gene expression in vitro and/or in vivo. This invention has therapeutic applications for neurological disorders such as ALS and FTD where altered expression of genes is part of the disease aetiology.

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